BDBM228269 US9555022, Example 02.08::US9555022, Example 02.28

SMILES COc1cc(ccc1Nc1nc2ccc(cn2n1)-c1ccc(NC(=O)Cc2ccc(F)cc2)cc1)N1CCN(C)CC1

InChI Key InChIKey=HQQWPMMOGVNUGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228269   

TargetDual specificity protein kinase TTK(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM228269(US9555022, Example 02.08 | US9555022, Example 02.2...)
Affinity DataIC50: <1nMpH: 7.7Assay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetDual specificity protein kinase TTK(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM228269(US9555022, Example 02.08 | US9555022, Example 02.2...)
Affinity DataIC50:  1.05nMpH: 7.7Assay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent