BDBM228457 BDBM229617::US9340506, G20A::US9556135, 102
SMILES CC1(C)C(N)=N[C@@](C)(CS1(=O)=O)c1cc(Oc2ccc3ccccc3c2)ccc1F
InChI Key InChIKey=NBHYVRPOYDEVFU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 228457
Affinity DataEC50: 64nMpH: 7.2Assay Description:The assay is carried out according to the protocol outlined in Hariharan et al (1997), Diabetes 46: 11-16. Briefly, the test compounds are incubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 140nMpH: 7.2Assay Description:The assay is carried out according to the protocol outlined in Hariharan et al (1997), Diabetes 46: 11-16. Briefly, the test compounds are incubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.35E+3nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
Affinity DataIC50: 5.12E+4nMpH: 3.5Assay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair