BDBM228617 US9345789, LI-0

SMILES CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)COC(=O)c1c(C)cccc1C

InChI Key InChIKey=VADLIPRWIKTOMS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 228617   

TargetLegumain(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM228617(US9345789, LI-0)
Affinity DataIC50: 11.5nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetLegumain(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM228617(US9345789, LI-0)
Affinity DataIC50: 145nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetLegumain(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM228617(US9345789, LI-0)
Affinity DataIC50: 704nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetCaspase-3(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM228617(US9345789, LI-0)
Affinity DataIC50: 2.80E+3nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetProcathepsin L(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM228617(US9345789, LI-0)
Affinity DataIC50: 1.00E+6nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetCathepsin B(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM228617(US9345789, LI-0)
Affinity DataIC50: 1.00E+6nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent