BDBM230252 US9340500, I-096

SMILES CNC(C)CCn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=IXIRGIJRPHFQES-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230252   

LigandPNGBDBM230252(US9340500, I-096)
Affinity DataKi:  130nM ΔG°:  -9.77kcal/mole IC50: 420nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent