BDBM230308 US9340507, 4.3

SMILES CC(C)n1cc(C(=O)NCc2nnc(C)o2)c(=O)c(-c2cccc(c2)C(F)F)c1C

InChI Key InChIKey=QJACYTSXWHPAJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230308   

TargetNeutrophil elastase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM230308(US9340507, 4.3)
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5, containing 0.01% BSA. Test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent