BDBM230684 US9340530, 21a::US9340530, 21b

SMILES C[C@H]1OC(=O)[C@@]2(CC(F)(F)C(C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)C12)C(O)c1nccs1

InChI Key InChIKey=XJZQLDPUCBXEFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 230684   

TargetProteinase-activated receptor 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM230684(US9340530, 21b | US9340530, 21a)
Affinity DataIC50: 1.20nMAssay Description:HEK 293 Cells were grown in media containing DMEM, 10% FBS pen/strep/L-Glutamine and non-essential amino acids. The cells were plated in 384-well PDL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent

TargetProteinase-activated receptor 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM230684(US9340530, 21b | US9340530, 21a)
Affinity DataIC50: 2.5nMAssay Description:HEK 293 Cells were grown in media containing DMEM, 10% FBS pen/strep/L-Glutamine and non-essential amino acids. The cells were plated in 384-well PDL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
US Patent