BDBM23083 7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hept-6-yn-1-one::CHEMBL367859::alpha-ketooxazole, 4qq

SMILES O=C(CCCCC#Cc1ccccc1)c1ncc(o1)-c1ccccn1

InChI Key InChIKey=BKXUCICJCJUBJI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23083   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23083(7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hept-...)
Affinity DataKi:  20nMAssay Description:Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA ligase 1(Human)
The Scripps Research Institute

LigandPNGBDBM23083(7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hept-...)
Affinity DataKi:  25nM ΔG°:  -10.4kcal/moleT: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2008
Entry Details Article
PubMed