BDBM2314 1,5-Diphenyl-3-(2-hydroxyethyl)-4-ethylpyrazole::1,5-Diphenyl-3-methylpyrazole (DPP) analogue 29::2-(4-ethyl-1,5-diphenyl-1H-pyrazol-3-yl)ethan-1-ol

SMILES CCc1c(CCO)nn(c1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=PFUUNMWVTPKJSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2314   

TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM2314(1,5-Diphenyl-3-(2-hydroxyethyl)-4-ethylpyrazole | ...)
Affinity DataIC50: 650nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM2314(1,5-Diphenyl-3-(2-hydroxyethyl)-4-ethylpyrazole | ...)
Affinity DataIC50: 5.00E+4nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2004
Entry Details Article
PubMed