BDBM23152 [(E)-[(3-{[4-(7-chloroquinolin-4-yl)piperazin-1-yl]methyl}-2,4-dihydroxyphenyl)methylidene]amino]thiourea::thiosemicarbazone derivative, 3f

SMILES NC(=S)NN=Cc1ccc(O)c(CN2CCN(CC2)c2ccnc3cc(Cl)ccc23)c1O

InChI Key InChIKey=SWLAWRRWOKPHSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23152   

TargetFalcipain 2(malaria parasite P. falciparum)
University of Cape Town

LigandPNGBDBM23152([(E)-[(3-{[4-(7-chloroquinolin-4-yl)piperazin-1-yl...)
Affinity DataIC50: 2.25E+3nMpH: 5.5 T: 2°CAssay Description:IC50 values against the recombinant falcipain-2 were determined by incubating protein with different concentrations of inhibitors in reaction buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed