BDBM232454 US9346795, 322

SMILES CCCCN(Cc1ccc(Cl)c(Cl)c1)c1ncc(Cl)c(n1)-c1ccc(cc1C(=O)N1CCc2ccccc2C1)C(=O)NS(=O)(=O)c1ccc2cccc(Cl)c2c1

InChI Key InChIKey=JHFWLESDNWOHBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 232454   

TargetApoptosis regulator Bcl-2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM232454(US9346795, 322)
Affinity DataIC50: 10nMT: 2°CAssay Description:The assays were performed in black flat-bottom 384-well plates. The final assay volume was 50 μl prepared from additions of Gst-Bcl-2 (Bcl-2: GE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM232454(US9346795, 322)
Affinity DataIC50: 160nMT: 2°CAssay Description:The assays were performed in black flat-bottom 384-well plates. The final assay volume was 55 μl prepared from additions of Biotin-Bcl-xL (Bcl-x...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
US Patent