BDBM233033 1-(4-(2-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine hydrochloride (B2-03)

SMILES CC1(C)N=C(N)N=C(N)N1c1ccc(OCc2ccccc2Cl)cc1

InChI Key InChIKey=BIPQHOMBJYCAJH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 233033   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute of Chemical Technology

LigandPNGBDBM233033(1-(4-(2-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50: 40nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute of Chemical Technology

LigandPNGBDBM233033(1-(4-(2-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50: 73nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute of Chemical Technology

LigandPNGBDBM233033(1-(4-(2-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50: 2.53E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute of Chemical Technology

LigandPNGBDBM233033(1-(4-(2-Chlorobenzyloxy)phenyl)-6,6-dimethyl-1,6-d...)
Affinity DataIC50: 1.03E+4nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed