BDBM233035 1-(4-(4-Bromobenzyloxy)phenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine hydrochloride (B2-05)

SMILES CC1(C)N=C(N)N=C(N)N1c1ccc(OCc2ccc(Br)cc2)cc1

InChI Key InChIKey=GMJSNOLKUZRASP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 233035   

TargetDihydrofolate reductase(Rat)
Institute of Chemical Technology

LigandPNGBDBM233035(1-(4-(4-Bromobenzyloxy)phenyl)-6,6-dimethyl-1,6-di...)
Affinity DataIC50: 33nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute of Chemical Technology

LigandPNGBDBM233035(1-(4-(4-Bromobenzyloxy)phenyl)-6,6-dimethyl-1,6-di...)
Affinity DataIC50: 33nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute of Chemical Technology

LigandPNGBDBM233035(1-(4-(4-Bromobenzyloxy)phenyl)-6,6-dimethyl-1,6-di...)
Affinity DataIC50: 829nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute of Chemical Technology

LigandPNGBDBM233035(1-(4-(4-Bromobenzyloxy)phenyl)-6,6-dimethyl-1,6-di...)
Affinity DataIC50: 7.32E+3nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed