BDBM234195 US9353090, 328::US9353090, 330

SMILES CO[C@@H]1CN(CC[C@@H]1C(O)=O)c1nc(cs1)-c1cc(F)cc(C)c1OCc1ccc2CCN(C[C@H](C)c2c1)C1CCOCC1

InChI Key InChIKey=ORYDFQUVEBFKPR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234195   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM234195(US9353090, 330 | US9353090, 328)
Affinity DataEC50:  2nMT: 2°CAssay Description:The sGC cellular activator assay is performed in the presence and absence of 50% human serum (HS) using Chinese hamster ovary cells that have been st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM234195(US9353090, 330 | US9353090, 328)
Affinity DataEC50:  5nMT: 2°CAssay Description:The sGC cellular activator assay is performed in the presence and absence of 50% human serum (HS) using Chinese hamster ovary cells that have been st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent