BDBM234514 US9353089, 166

SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCN(C)CC2)C1=O)c1ccc(OC)cc1

InChI Key InChIKey=NEZMJXSOLFCLPF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 234514   

TargetPlasmepsin II(Plasmodium falciparum)
Saint Louis University

US Patent
LigandPNGBDBM234514(US9353089, 166)
Affinity DataIC50: 34.7nMpH: 4.5 T: 2°CAssay Description:Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetPlasmepsin II(Plasmodium falciparum)
Saint Louis University

US Patent
LigandPNGBDBM234514(US9353089, 166)
Affinity DataIC50: 35nMpH: 4.5 T: 2°CAssay Description:Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetPlasmepsin IV [1-448](malaria parasite P. falciparum)
Saint Louis University

US Patent
LigandPNGBDBM234514(US9353089, 166)
Affinity DataIC50: 109nMpH: 4.5 T: 2°CAssay Description:Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent