BDBM23503 beta-sulfonyl hydroxamate analogue, 11::tert-butyl 4-[({4-[but-2-yn-1-yl(methyl)amino]benzene}sulfonyl)methyl]-4-(hydroxycarbamoyl)piperidine-1-carboxylate

SMILES CC#CCN(C)c1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)OC(C)(C)C)C(=O)NO

InChI Key InChIKey=VYJYRILYFYRPCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23503   

LigandPNGBDBM23503(tert-butyl 4-[({4-[but-2-yn-1-yl(methyl)amino]benz...)
Affinity DataIC50: 3.30nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit the cleavage of the substrate by the purified enzyme in a fluorescence-based fluorescence resonanc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2008
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

LigandPNGBDBM23503(tert-butyl 4-[({4-[but-2-yn-1-yl(methyl)amino]benz...)
Affinity DataIC50: 1.60E+3nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit the cleavage of the substrate by the purified enzyme in a fluorescence-based fluorescence resonanc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2008
Entry Details Article
PubMed