BDBM235083 4-[8-[4-(dimethylamino)piperidin-1-yl]-5-(1-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)imidazo[1,5-a]pyrazin-6-yl]benzonitrile::US10047086, 50

SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)[N+]#[C-])c(-c2cnc3n(C)ncc3c2)n2cncc12

InChI Key InChIKey=MGLWEWRURIGUTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235083   

TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM235083(4-[8-[4-(dimethylamino)piperidin-1-yl]-5-(1-methyl...)
Affinity DataIC50: 50nMpH: 7.5Assay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
US Patent