BDBM235281 US10085990, Example 4::US9393245, 4

SMILES CCn1c(=O)n(-c2ccc(OC)c(OC)c2)c2c3cccc(OC)c3ncc2c1=O

InChI Key InChIKey=HBWXXRCASVTUIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235281   

LigandChemical structure of BindingDB Monomer ID 235281BDBM235281(US9393245, 4 | US10085990, Example 4)
Affinity DataIC50: 1.42E+4nMAssay Description:Samples were tested for TNF as per the manufacturer's instructions (TNF ELISA; R&D Systems, Cat #DY210). The samples were serially diluted with P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Vtv Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 235281BDBM235281(US9393245, 4 | US10085990, Example 4)
Affinity DataIC50: 1.42E+4nMT: 2°CAssay Description:Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent