BDBM235636 (E)-1-(3-hydroxyphenyl)-3-(2-hydroxyphenyl)-2-propen-1-one (10)

SMILES Oc1cccc(c1)C(=O)\C=C\c1ccccc1O

InChI Key InChIKey=KAMRNYCNWDARJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235636   

TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandPNGBDBM235636((E)-1-(3-hydroxyphenyl)-3-(2-hydroxyphenyl)-2-prop...)
Affinity DataIC50: 3.04E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed