BDBM235639 (E)-1-(2,6-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-propen-1-one (14)

SMILES Oc1ccccc1\C=C\C(=O)c1c(O)cccc1O

InChI Key InChIKey=XENAJIPPWSRKAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235639   

TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandPNGBDBM235639((E)-1-(2,6-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)
Affinity DataIC50: 1.56E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed