BDBM235645 (E)-1-(2,4-dihydroxyphenyl)-3-(3,5-dihydroxyphenyl)-2-propen-1-one (22)

SMILES Oc1ccc(C(=O)\C=C\c2cc(O)cc(O)c2)c(O)c1

InChI Key InChIKey=ZSMOFGFLBCKTKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235645   

TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandPNGBDBM235645((E)-1-(2,4-dihydroxyphenyl)-3-(3,5-dihydroxyphenyl...)
Affinity DataIC50: 2.08E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM235645((E)-1-(2,4-dihydroxyphenyl)-3-(3,5-dihydroxyphenyl...)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in uric acid level measured after 15 mins by spectrophotometric analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed