BDBM235696 L-Isoseryl-L-leucine methyl ester hydrochloride (11b)

SMILES COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)CN

InChI Key InChIKey=MWFLBYFOZYTYEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235696   

TargetAminopeptidase N(Pig)
Shandong University

LigandPNGBDBM235696(L-Isoseryl-L-leucine methyl ester hydrochloride (1...)
Affinity DataIC50: 2.29E+5nMAssay Description:The samples and positive controls were serial diluted to various concentrations: 1280 μg/mL, 320 μg/mL, 80 μg/mL, and 20 μg/mL, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Shandong University

LigandPNGBDBM235696(L-Isoseryl-L-leucine methyl ester hydrochloride (1...)
Affinity DataIC50: 6.82E+5nMpH: 8.5 T: 2°CAssay Description:The compound samples were assayed for inhibitory activity against MMP-2 in 96-well microplates using succinylated gelatin as the substrate. The compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed