BDBM235932 US9365529, 20

SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)C(=O)NO)c2ccccc2n1

InChI Key InChIKey=JCBLZSWVZUEGKV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 235932   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM235932(US9365529, 20)
Affinity DataIC50: 140nMpH: 7.4 T: 2°CAssay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetInterstitial collagenase(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM235932(US9365529, 20)
Affinity DataIC50: 3.94E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetStromelysin-1(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM235932(US9365529, 20)
Affinity DataIC50: 4.78E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM235932(US9365529, 20)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetMatrix metalloproteinase-9(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM235932(US9365529, 20)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 9(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM235932(US9365529, 20)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent