BDBM236561 US9365572, 30

SMILES FC(F)(F)c1cccc(c1)-n1c2c(cnc3ccc(nc23)-c2cnc3[nH]ccc3c2)c(=O)[nH]c1=O

InChI Key InChIKey=VVVPWJKRDCCYGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236561   

TargetSerine/threonine-protein kinase mTOR(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM236561(US9365572, 30)
Affinity DataIC50: 1.12nMpH: 7.5 T: 2°CAssay Description:Agents: 1-fold kinase buffer: 50 mM HEPES, pH 7.5, 10 mM MgCl2, 1 mM EGTA, 3 mM MnCl2, 0.01% Tween-20, 2 mM DTT. 4-fold kinase solution: mTOR kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM236561(US9365572, 30)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:Agents: 1-fold kinase buffer: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS, 2 mM DTT). 4-fold kinase solution: PI3K ± kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent