BDBM236626 US9388136, Table 1, Compound 18:Cyclopentyl N- [2-(4-{6-amino- 5-[(2,4-difluoro- phenyl)carbonyl]- 2-oxopyridin- 1(2H)-yl}-3,5 difluorophenyl) ethyl]-L-valinate

SMILES CC(C)[C@H](NCCc1cc(F)c(c(F)c1)-n1c(N)c(ccc1=O)C(=O)c1ccc(F)cc1F)C(=O)OC1CCCC1

InChI Key InChIKey=PZLMULRZZKUVNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236626   

TargetMitogen-activated protein kinase 14(Human)
Chroma Therapeutics

US Patent
LigandPNGBDBM236626(US9388136, Table 1, Compound 18:Cyclopentyl N- [2-...)
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent