BDBM236633 US9388136, Table 1, Compound 25:Cyclopentyl (2R)- [(2-{4-[6-amino- 5-(2,4-difluoro- benzoyl)-2- oxopyridin- 1(2H)-yl]-3,5- difluorophenyl} ethyl)amino] (phenyl)acetate

SMILES Nc1c(ccc(=O)n1-c1c(F)cc(CCN[C@@H](C(=O)OC2CCCC2)c2ccccc2)cc1F)C(=O)c1ccc(F)cc1F

InChI Key InChIKey=XARADUFHWOHIKA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236633   

TargetMitogen-activated protein kinase 14(Human)
Chroma Therapeutics

US Patent
LigandPNGBDBM236633(US9388136, Table 1, Compound 25:Cyclopentyl (2R)- ...)
Affinity DataIC50: 47nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2017
Entry Details
US Patent