BDBM237160 US9394307, 4-chloro-N-(5-chloro-2-{7H-pyrrolo[2,3-d]pyrimidine-4-carbonyl}pyridin-3-yl)-3-(trifluoromethyl)benzene-1-sulfonamide

SMILES FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)Nc1cc(Cl)cnc1C(=O)c1ncnc2[nH]ccc12

InChI Key InChIKey=QGSSAWJOQFRMTB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237160   

TargetCytochrome P450 2C9(Human)
Chemocentryx

US Patent
LigandPNGBDBM237160(US9394307, 4-chloro-N-(5-chloro-2-{7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.50E+4nMT: 2°CAssay Description:The test compounds were incubated with pooled human liver microsomes at 37° C. in the presence of NADPH and appropriate concentrations of substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent