BDBM237283 Carbonic anhydrase inhibitors (CAIs), 4

SMILES Cc1ccc(cc1)S(=O)(=O)N1[C@@H]2C=CCC[C@@H]2OC1(C)C

InChI Key InChIKey=GDCXSEXLPRSTKI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 237283   

TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM237283(Carbonic anhydrase inhibitors (CAIs), 4)
Affinity DataKi:  2.17E+4nMpH: 7.4Assay Description:The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 3(Bovine)
Ondokuz Mayis University

LigandPNGBDBM237283(Carbonic anhydrase inhibitors (CAIs), 4)
Affinity DataKi:  5.74E+4nMpH: 7.4Assay Description:The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ondokuz Mayis University

LigandPNGBDBM237283(Carbonic anhydrase inhibitors (CAIs), 4)
Affinity DataKi:  2.75E+5nMpH: 7.4Assay Description:The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM237283(Carbonic anhydrase inhibitors (CAIs), 4)
Affinity DataKi:  3.79E+5nMpH: 7.4Assay Description:The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed