BDBM237509 US9393232, 2.10a::US9393232, 2.10b

SMILES C[C@H](CO)NC1(C(=O)Nc2ccc(cc12)-c1c(C)noc1C)c1ccccc1

InChI Key InChIKey=JQGLKQWMMRCIIG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 237509   

TargetBromodomain-containing protein 3 [1-435](Human)
Beigene

US Patent
LigandPNGBDBM237509(US9393232, 2.10b | US9393232, 2.10a)
Affinity DataIC50: 23nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetBromodomain-containing protein 2 [1-473](Human)
Beigene

US Patent
LigandPNGBDBM237509(US9393232, 2.10b | US9393232, 2.10a)
Affinity DataIC50: 24nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [1-477](Human)
Beigene

US Patent
LigandPNGBDBM237509(US9393232, 2.10b | US9393232, 2.10a)
Affinity DataIC50: 57nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetBromodomain testis-specific protein [1-397](Human)
Beigene

US Patent
LigandPNGBDBM237509(US9393232, 2.10b | US9393232, 2.10a)
Affinity DataIC50: 69nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [1-477](Human)
Beigene

US Patent
LigandPNGBDBM237509(US9393232, 2.10b | US9393232, 2.10a)
Affinity DataIC50: 370nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent