BDBM238017 US9394285, 103

SMILES OC(=O)c1n[nH]c2cc(Cl)c(cc12)-c1ccc(cc1)C1(O)CCC1

InChI Key InChIKey=KRYYLQKIPMTRNQ-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238017   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM238017(US9394285, 103)Copy SMILESCopy InChI

Affinity DataEC50:  8.30nMAssay Description:Activation of full length human phosphorylated His-tagged AMPK alpha1/beta1/gamma1 expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL using SAMS...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/9/2018
Entry Details Article
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Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM238017(US9394285, 103)Copy SMILESCopy InChI

Affinity DataEC50:  8.30nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/17/2017
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL