BDBM238545 US9394297, 191
SMILES CCCNc1nc2c(cccc2nc1C)-c1cc2c(CCNC2=O)[nH]1
InChI Key InChIKey=QTIQZQUAJDJRAA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 238545
Affinity DataIC50: 9.30nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human full-length Pim2 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser 112 preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human full-length Pim1 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser-112 preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair