BDBM238573 US9394297, 220

SMILES CCN(c1cnc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2n1)C(C)(C)C

InChI Key InChIKey=PCKUZAUQQUCSJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238573   

TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

US Patent
LigandPNGBDBM238573(US9394297, 220)
Affinity DataIC50: 0.100nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

US Patent
LigandPNGBDBM238573(US9394297, 220)
Affinity DataIC50: 0.100nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent