BDBM23870 3-[(2S)-3-[4-(4-carbamimidamidobutanoyl)piperazin-1-yl]-3-oxo-2-{[2,4,6-tris(propan-2-yl)benzene]sulfonamido}propyl]benzene-1-carboximidamide::3-amidinophenylalanine deriv., 14

SMILES [#6]-[#6](-[#6])-c1cc(-[#6](-[#6])-[#6])c(c(c1)-[#6](-[#6])-[#6])S(=O)(=O)[#7]-[#6@@H](-[#6]-c1cccc(c1)-[#6](-[#7])=[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7]

InChI Key InChIKey=GKEDWEKWBQHEDD-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23870   

TargetSuppressor of tumorigenicity 14 protein(Human)
Curacyte Chemistry

LigandPNGBDBM23870(3-[(2S)-3-[4-(4-carbamimidamidobutanoyl)piperazin-...)
Affinity DataKi:  61nM ΔG°:  -9.84kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Chemistry

LigandPNGBDBM23870(3-[(2S)-3-[4-(4-carbamimidamidobutanoyl)piperazin-...)
Affinity DataKi:  260nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Chemistry

LigandPNGBDBM23870(3-[(2S)-3-[4-(4-carbamimidamidobutanoyl)piperazin-...)
Affinity DataKi:  880nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Curacyte Chemistry

LigandPNGBDBM23870(3-[(2S)-3-[4-(4-carbamimidamidobutanoyl)piperazin-...)
Affinity DataKi:  2.80E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Curacyte Chemistry

LigandPNGBDBM23870(3-[(2S)-3-[4-(4-carbamimidamidobutanoyl)piperazin-...)
Affinity DataKi:  4.20E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed