BDBM238803 US9394297, 490

SMILES CC(C)Nc1nc2c(-c3cc4C(=O)N[C@H](C)c4[nH]3)c(F)ccc2c(=O)n1C1CC1

InChI Key InChIKey=YWQCLSBVOVPANW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238803   

TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

US Patent
LigandPNGBDBM238803(US9394297, 490)
Affinity DataIC50: 0.100nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

US Patent
LigandPNGBDBM238803(US9394297, 490)
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent