BDBM238829 US9403768, 1

SMILES CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](C(=O)Nc2c(F)cccc2F)C(C)(C)c2ccccc12

InChI Key InChIKey=JVKFCLCUILQTAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238829   

TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche

US Patent
LigandPNGBDBM238829(US9403768, 1)
Affinity DataIC50: 21.2nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM238829(US9403768, 1)
Affinity DataIC50: 5.48E+4nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent