BDBM23886 3-[(2S)-3-oxo-3-[4-(piperidin-4-ylcarbonyl)piperazin-1-yl]-2-{[2,4,6-tris(propan-2-yl)benzene]sulfonamido}propyl]benzene-1-carboximidamide::3-amidinophenylalanine deriv., 30

SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)C(=O)C1CCNCC1

InChI Key InChIKey=XKXAXFJNQDWDNX-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 23886   

TargetSuppressor of tumorigenicity 14 protein(Human)
Curacyte Chemistry

LigandPNGBDBM23886(3-[(2S)-3-oxo-3-[4-(piperidin-4-ylcarbonyl)piperaz...)
Affinity DataKi:  100nM ΔG°:  -9.54kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Curacyte Chemistry

LigandPNGBDBM23886(3-[(2S)-3-oxo-3-[4-(piperidin-4-ylcarbonyl)piperaz...)
Affinity DataKi:  120nMAssay Description:Inhibition of matripase (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Chemistry

LigandPNGBDBM23886(3-[(2S)-3-oxo-3-[4-(piperidin-4-ylcarbonyl)piperaz...)
Affinity DataKi:  1.20E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Chemistry

LigandPNGBDBM23886(3-[(2S)-3-oxo-3-[4-(piperidin-4-ylcarbonyl)piperaz...)
Affinity DataKi:  1.30E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Curacyte Chemistry

LigandPNGBDBM23886(3-[(2S)-3-oxo-3-[4-(piperidin-4-ylcarbonyl)piperaz...)
Affinity DataKi:  5.40E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM23886(3-[(2S)-3-oxo-3-[4-(piperidin-4-ylcarbonyl)piperaz...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells using Boc-QLR-AMC as substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM23886(3-[(2S)-3-oxo-3-[4-(piperidin-4-ylcarbonyl)piperaz...)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of hepsin (unknown origin) using Boc-QAR-AMC as substrate after 30 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Curacyte Chemistry

LigandPNGBDBM23886(3-[(2S)-3-oxo-3-[4-(piperidin-4-ylcarbonyl)piperaz...)
Affinity DataKi:  1.70E+4nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed