BDBM23899 3-[(2S)-2-[(4-cyclohexylbenzene)sulfonamido]-3-oxo-3-[4-(piperazin-1-ylcarbonyl)piperidin-1-yl]propyl]benzene-1-carboximidamide::3-amidinophenylalanine deriv., 43

SMILES NC(=N)c1cccc(C[C@H](NS(=O)(=O)c2ccc(cc2)C2CCCCC2)C(=O)N2CCC(CC2)C(=O)N2CCNCC2)c1

InChI Key InChIKey=LTNXXFHVQLJQHO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23899   

TargetProthrombin(Bovine)
Curacyte Chemistry

LigandPNGBDBM23899(3-[(2S)-2-[(4-cyclohexylbenzene)sulfonamido]-3-oxo...)
Affinity DataKi:  170nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Curacyte Chemistry

LigandPNGBDBM23899(3-[(2S)-2-[(4-cyclohexylbenzene)sulfonamido]-3-oxo...)
Affinity DataKi:  240nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Curacyte Chemistry

LigandPNGBDBM23899(3-[(2S)-2-[(4-cyclohexylbenzene)sulfonamido]-3-oxo...)
Affinity DataKi:  1.10E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Chemistry

LigandPNGBDBM23899(3-[(2S)-2-[(4-cyclohexylbenzene)sulfonamido]-3-oxo...)
Affinity DataKi:  2.80E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Chemistry

LigandPNGBDBM23899(3-[(2S)-2-[(4-cyclohexylbenzene)sulfonamido]-3-oxo...)
Affinity DataKi:  6.60E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed