BDBM23916 3-amidinophenylalanine deriv., 12::3-amino-N-(3-{[(2S)-1-[4-(2-carbamimidamidoethyl)piperidin-1-yl]-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl]sulfamoyl}phenyl)propanamide::CHEMBL378657

SMILES [#7]-[#6]-[#6]-[#6](=O)-[#7]-c1cccc(c1)S(=O)(=O)[#7]-[#6@@H](-[#6]-c1cccc(c1)-[#6](-[#7])=[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6]-[#6]-1

InChI Key InChIKey=LGZLMJONOIAQLM-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 23916   

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM23916(CHEMBL378657 | 3-amino-N-(3-{[(2S)-1-[4-(2-carbami...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM23916(CHEMBL378657 | 3-amino-N-(3-{[(2S)-1-[4-(2-carbami...)
Affinity DataKi:  1.80nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Chemistry

LigandPNGBDBM23916(CHEMBL378657 | 3-amino-N-(3-{[(2S)-1-[4-(2-carbami...)
Affinity DataKi:  1.70E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Chemistry

LigandPNGBDBM23916(CHEMBL378657 | 3-amino-N-(3-{[(2S)-1-[4-(2-carbami...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Chemistry

LigandPNGBDBM23916(CHEMBL378657 | 3-amino-N-(3-{[(2S)-1-[4-(2-carbami...)
Affinity DataKi:  5.00E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Chemistry

LigandPNGBDBM23916(CHEMBL378657 | 3-amino-N-(3-{[(2S)-1-[4-(2-carbami...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM23916(CHEMBL378657 | 3-amino-N-(3-{[(2S)-1-[4-(2-carbami...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Curacyte Chemistry

LigandPNGBDBM23916(CHEMBL378657 | 3-amino-N-(3-{[(2S)-1-[4-(2-carbami...)
Affinity DataKi:  6.00E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Curacyte Chemistry

LigandPNGBDBM23916(CHEMBL378657 | 3-amino-N-(3-{[(2S)-1-[4-(2-carbami...)
Affinity DataKi:  9.50E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM23916(CHEMBL378657 | 3-amino-N-(3-{[(2S)-1-[4-(2-carbami...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed