BDBM239850 Roche-Dataset for PDE10A, Compound 83::US9394311, 131

SMILES Cc1c(Cl)cc(c2nc(CCc3nc(N4CCCC4)n(n3)C3CC3)nn12)C(F)(F)F

InChI Key InChIKey=VBWTUCQJMXHYNI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239850   

LigandPNGBDBM239850(US9394311, 131 | Roche-Dataset for PDE10A, Compoun...)
Affinity DataIC50: 1.58nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

LigandPNGBDBM239850(US9394311, 131 | Roche-Dataset for PDE10A, Compoun...)
Affinity DataIC50: 1.58nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details Article
PubMed