BDBM239870 US9403767, 25::US9403767, 28

SMILES CN(C)C1(CCC(CC1)(N(C)C(C)=O)c1ccccc1)c1ccccc1

InChI Key InChIKey=IAPPMVYMEDGDEU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 239870   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239870(US9403767, 28 | US9403767, 25)
Affinity DataKi:  15.4nM ΔG°:  -10.7kcal/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239870(US9403767, 28 | US9403767, 25)
Affinity DataKi:  190nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239870(US9403767, 28 | US9403767, 25)
Affinity DataKi:  895nM ΔG°:  -8.25kcal/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239870(US9403767, 28 | US9403767, 25)
Affinity DataKi:  1.01E+3nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent