BDBM239886 US9403767, 44

SMILES CN(C)C1(CCC(C)(CNS(=O)(=O)\C=C\c2ccccc2)CC1)c1cccc(F)c1

InChI Key InChIKey=VOSYFPMXKBHSQB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239886   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239886(US9403767, 44)
Affinity DataKi:  13.3nM ΔG°:  -10.7kcal/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239886(US9403767, 44)
Affinity DataKi:  77.5nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent