BDBM239897 US9403767, 60::US9403767, 61

SMILES CNC1(CCC(CC2CCCC2)(CC1)N(C)C)c1ccccc1

InChI Key InChIKey=CWCGLOZQTFJHDB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 239897   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239897(US9403767, 61 | US9403767, 60)
Affinity DataKi:  32nM ΔG°:  -10.2kcal/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239897(US9403767, 61 | US9403767, 60)
Affinity DataKi:  107nM ΔG°:  -9.50kcal/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239897(US9403767, 61 | US9403767, 60)
Affinity DataKi:  375nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239897(US9403767, 61 | US9403767, 60)
Affinity DataKi:  530nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent