BDBM239977 US9403801, 48

SMILES Clc1cnc(Nc2cnn(CC3CC3)c2)nc1NC1CCC2(CC1)CCN(CC2)C(=O)CC#N

InChI Key InChIKey=TZZRXEHUMVJDQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 239977   

TargetTyrosine-protein kinase JAK1(Human)
Calitor Sciences

US Patent
LigandPNGBDBM239977(US9403801, 48)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:JAK1 (h) is incubated with 20 mM Tris/HCl pH 7.5, 0.2 mM EDTA, 500 μM GEEPLYWSFPAKKK, 10 mM MgAcetate and [γ-33P-ATP](specific activity app...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent