BDBM240259 US9403843, 36

SMILES Cn1cnc(C[C@H](NC(=O)[C@H]2O[C@@H]2C(O)=O)C(=O)Nc2nc(cs2)-c2ccc(F)cc2)c1

InChI Key InChIKey=LJVYKEXBMLFVRZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 240259   

TargetCalpain-1 catalytic subunit(Human)
Columbia University

US Patent
LigandPNGBDBM240259(US9403843, 36)
Affinity DataIC50: 225nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent