BDBM241669 US9409915, 65

SMILES Cn1nc(c(C#N)c1-c1nc2nc(cc(N3CCOCC3)c2[nH]1)-c1ccccc1C(F)(F)F)C(C)(C)C

InChI Key InChIKey=IBARVXFDNKJHMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 241669   

TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM241669(US9409915, 65)
Affinity DataIC50: 3.20nMT: 2°CAssay Description:HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, 2 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent