BDBM242686 US9422290, III-5::US9422290, III-7

SMILES CN(C)CCCS(=O)(=O)N1CCC(CC1)Nc1cc(nn2c(C)nnc12)N(C)Cc1ccccc1

InChI Key InChIKey=PKELZFOCBUGMPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 242686   

TargetBromodomain-containing protein 4 [44-168](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM242686(US9422290, III-7 | US9422290, III-5)
Affinity DataIC50: 37nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM242686(US9422290, III-7 | US9422290, III-5)
Affinity DataIC50: 57nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
US Patent