BDBM243364 4-{5-[2-Methyl-3-(4- methyl-pyrimidin-2- ylamino)-pheny]-oxazol- 2-yl}-4,7-diaza- spiro[2.5]octan-8-one::US10053455, 020

SMILES Cc5ccnc(Nc4cccc(c3cnc(N1CCNC(=O)C12CC2)o3)c4C)n5

InChI Key InChIKey=XSXYCYUFZSPGRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243364   

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243364(4-{5-[2-Methyl-3-(4- methyl-pyrimidin-2- ylamino)-...)
Affinity DataIC50: 2.00E+3nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
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Date in BDB:
10/18/2018
Entry Details
US Patent