BDBM243366 4-{5-[3-(Thiazol-2- ylamino)-phenyl]oxazol- 2-yl}-4,7-diaza- spiro[2.5]octan-8-one::US10053455, 022

SMILES O=C1NCCN(c2ncc(o2)-c2cccc(Nc3nccs3)c2)C11CC1

InChI Key InChIKey=RAYTWKUFSLXLJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243366   

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243366(4-{5-[3-(Thiazol-2- ylamino)-phenyl]oxazol- 2-yl}-...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent