BDBM243396 5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-methoxy-1-isopropyl-1,2,3,4-tetrahydroisoquinolin-6-yl)pyrimidine-2,4-diamine::US10053458, 28

SMILES COc1cc2C(NCCc2cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)C(C)C

InChI Key InChIKey=ZJAUCUAXUZZZGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 243396   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM243396(5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-met...)
Affinity DataIC50: <10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM243396(5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-met...)
Affinity DataIC50: <10nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent