BDBM245619 US9428508, 74

SMILES CNC(=O)c1cccc(Nc2nc3NCCc3c(Nc3ccccc3S(=O)(=O)NC(C)C)n2)c1

InChI Key InChIKey=OFQMYGWFTGXFND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245619   

TargetFocal adhesion kinase 1(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM245619(US9428508, 74)
Affinity DataIC50: 20nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetProtein-tyrosine kinase 2-beta(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM245619(US9428508, 74)
Affinity DataIC50: 50nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent