BDBM245876 US9428514, 64

SMILES CCOc1cc(=O)n(C)cc1-c1cc(NCc2ccc(F)cc2)ccc1Oc1ccc(F)cc1F

InChI Key InChIKey=YVUKZBQRWODYJF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245876   

TargetBromodomain-containing protein 4 [352-457](Human)
Abbvie

US Patent
LigandPNGBDBM245876(US9428514, 64)
Affinity DataKi:  61.8nM ΔG°:  -9.83kcal/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [57-168](Human)
Abbvie

US Patent
LigandPNGBDBM245876(US9428514, 64)
Affinity DataKi: >238nM ΔG°: >-9.03kcal/molepH: 6.0 T: 2°CAssay Description:Assay method C: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.047 mM to 0.7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent